Most house buyers have many fears when getting ready to buy a home, whether it is the first time buyer or a couple who have bought and sold 5 homes in their lifetime.
Most of those fears are normal and that is a good thing. However:
I have worked with hundreds of home buyers over the years and I have found that most of their fears were of the unknown or worst of all, here say by family, friends and co-workers. My role as a professional Realtor is to address those fears, acknowledge them and then overcome those fears with factual information, not my perceptions but the real world of real estate reality.
The fear of buying the wrong house, over-paying for it, defects, financing and location can in 99% of the time, can be overcome with due diligence.
The fear of being happy in that home, entertaining and appreciating in value is internal and way above my paygrade to offer advice!
In the end, common sense, being practical and keeping your emotions in check will be your best friends.